Description
Product Characteristics: Synonyms: KIAA1547
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES(By similarity).
Target Information: may be involved in transcription regulation in the CNS both during development and in the adult